DDAH1 regulates apoptosis and angiogenesis in human fetal pulmonary microvascular endothelial cells
Abstract Nitric Oxide (NO) is an endogenous pulmonary vasodilator produced by endothelial NO synthase (eNOS). Asymmetric dimethyl L‐arginine (ADMA) is an endogenous inhibitor of eNOS activity. In endothelial cells, ADMA is hydrolyzed to L‐citrulline primarily by dimethylarginine dimethyl‐aminohydrol...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
Wiley
2019-06-01
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Series: | Physiological Reports |
Subjects: | |
Online Access: | https://doi.org/10.14814/phy2.14150 |