THE MECHANISMS OF PROTONATION OF EXTRACELLULAR MATRIX IN TUMORS

THE MECHANISMS OF PROTONATION OF EXTRACELLULAR MATRIX IN TUMORS

One of the differences between normal and tumor cells is more intensive acidification of the extracellular area in tumor cells compare with intracellular area. Low pH in extracellular region stimulates invasion and metastatic process. This effect of low pH is not fully understood. There are some mec...

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Bibliographic Details
Main Author: V. A. Koblyakov
Format: Article
Language:Russian
Published: ABV-press 2015-12-01
Series:Uspehi Molekulârnoj Onkologii
Subjects:
invasion and metastasis, lactate dehydrogenase, monocarboxilate transporter, carbonic anhydrase, na+/h+ exchanger, hypoxia, glycolysis, hif-1α
Online Access:https://umo.abvpress.ru/jour/article/view/42

Internet

https://umo.abvpress.ru/jour/article/view/42

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