Live attenuated Rev-independent Nef¯SIV enhances acquisition of heterologous SIVsmE660 in acutely vaccinated rhesus macaques.

Rhesus macaques (RMs) inoculated with live-attenuated Rev-Independent Nef¯ simian immunodeficiency virus (Rev-Ind Nef¯SIV) as adults or neonates controlled viremia to undetectable levels and showed no signs of immunodeficiency over 6-8 years of follow-up. We tested the capacity of this live-attenuat...

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Main Authors: Siddappa N Byrareddy, Mila Ayash-Rashkovsky, Victor G Kramer, Sandra J Lee, Mick Correll, Francis J Novembre, Francois Villinger, Welkin E Johnson, Agneta von Gegerfelt, Barbara K Felber, Ruth M Ruprecht
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3787041?pdf=render