Influence of maternal zinc supplementation on the development of autism-associated behavioural and synaptic deficits in offspring Shank3-knockout mice

Abstract Autism Spectrum Disorders (ASD) are characterised by deficits in social interactions and repetitive behaviours. Multiple ASD-associated mutations have been identified in the Shank family of proteins that play a critical role in the structure and plasticity of glutamatergic synapses, leading...

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Bibliographic Details
Main Authors: Yukti Vyas, Kevin Lee, Yewon Jung, Johanna M. Montgomery
Format: Article
Language:English
Published: BMC 2020-08-01
Series:Molecular Brain
Subjects:
Online Access:http://link.springer.com/article/10.1186/s13041-020-00650-0