Influence of maternal zinc supplementation on the development of autism-associated behavioural and synaptic deficits in offspring Shank3-knockout mice
Abstract Autism Spectrum Disorders (ASD) are characterised by deficits in social interactions and repetitive behaviours. Multiple ASD-associated mutations have been identified in the Shank family of proteins that play a critical role in the structure and plasticity of glutamatergic synapses, leading...
Main Authors: | Yukti Vyas, Kevin Lee, Yewon Jung, Johanna M. Montgomery |
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Format: | Article |
Language: | English |
Published: |
BMC
2020-08-01
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Series: | Molecular Brain |
Subjects: | |
Online Access: | http://link.springer.com/article/10.1186/s13041-020-00650-0 |
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