Implementation of Multigene Germline and Parallel Somatic Genetic Testing in Epithelial Ovarian Cancer: SIGNPOST Study

Implementation of Multigene Germline and Parallel Somatic Genetic Testing in Epithelial Ovarian Cancer: SIGNPOST Study

We present findings of a cancer multidisciplinary-team (MDT) coordinated mainstreaming pathway of unselected 5-panel germline <i>BRCA1/BRCA2/RAD51C/RAD51D/BRIP1</i> and parallel somatic <i>BRCA1/BRCA2</i> testing in all women with epithelial-OC and highlight the discordance b...

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Bibliographic Details
Main Authors: Dhivya Chandrasekaran, Monika Sobocan, Oleg Blyuss, Rowan E. Miller, Olivia Evans, Shanthini M. Crusz, Tina Mills-Baldock, Li Sun, Rory F. L. Hammond, Faiza Gaba, Lucy A. Jenkins, Munaza Ahmed, Ajith Kumar, Arjun Jeyarajah, Alexandra C. Lawrence, Elly Brockbank, Saurabh Phadnis, Mary Quigley, Fatima El Khouly, Rekha Wuntakal, Asma Faruqi, Giorgia Trevisan, Laura Casey, George J. Burghel, Helene Schlecht, Michael Bulman, Philip Smith, Naomi L. Bowers, Rosa Legood, Michelle Lockley, Andrew Wallace, Naveena Singh, D. Gareth Evans, Ranjit Manchanda
Format: Article
Language:English
Published: MDPI AG 2021-08-01
Series:Cancers
Subjects:
ovarian cancer
<i>BRCA</i>
genetic testing
germline
somatic
<i>RAD51C</i>
Online Access:https://www.mdpi.com/2072-6694/13/17/4344

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https://www.mdpi.com/2072-6694/13/17/4344

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