Discovery of tanshinone derivatives with anti-MRSA activity via targeted bio-transformation
Two potent anti-MRSA tanshinone glycosides (1 and 2) were discovered by targeted microbial biotransformation, along with rapid identification via MS/MS networking. Serial reactions including dehydrogenation, demethylations, reduction, glycosylation and methylation have been observed after incubation...
Main Authors: | , , , , , , , , , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
KeAi Communications Co., Ltd.
2016-09-01
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Series: | Synthetic and Systems Biotechnology |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2405805X15300223 |