The cumulative effect of small vessel disease lesions is reflected in structural brain networks of memory clinic patients

Background and purpose: Mechanisms underlying cognitive impairment in patients with small vessel disease (SVD) are still unknown. We hypothesized that cognition is affected by the cumulative effect of multiple SVD-related lesions on brain connectivity. We therefore assessed the relationship between...

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Bibliographic Details
Main Authors: Rutger Heinen, Naomi Vlegels, Jeroen de Bresser, Alexander Leemans, Geert Jan Biessels, Yael D. Reijmer
Format: Article
Language:English
Published: Elsevier 2018-01-01
Series:NeuroImage: Clinical
Online Access:http://www.sciencedirect.com/science/article/pii/S2213158218302080