The Development of a Recombinant scFv Monoclonal Antibody Targeting Canine CD20 for Use in Comparative Medicine.

The Development of a Recombinant scFv Monoclonal Antibody Targeting Canine CD20 for Use in Comparative Medicine.

Monoclonal antibodies are leading agents for therapeutic treatment of human diseases, but are limited in use by the paucity of clinically relevant models for validation. Sporadic canine tumours mimic the features of some human equivalents. Developing canine immunotherapeutics can be an approach for...

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Bibliographic Details
Main Authors: Saurabh Jain, Luca Aresu, Stefano Comazzi, Jianguo Shi, Erin Worrall, John Clayton, William Humphries, Sandra Hemmington, Paul Davis, Euan Murray, Asmare A Limeneh, Kathryn Ball, Eva Ruckova, Petr Muller, Borek Vojtesek, Robin Fahraeus, David Argyle, Ted R Hupp
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4760772?pdf=render

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http://europepmc.org/articles/PMC4760772?pdf=render

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