Probable impact of age and hypoxia on proliferation and microRNA expression profile of bone marrow-derived human mesenchymal stem cells
Decline in the therapeutic potential of bone marrow-derived mesenchymal stem cells (MSC) is often seen with older donors as compared to young. Although hypoxia is known as an approach to improve the therapeutic potential of MSC in term of cell proliferation and differentiation capacity, its effects...
Main Authors: | , , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
PeerJ Inc.
2016-01-01
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Series: | PeerJ |
Subjects: | |
Online Access: | https://peerj.com/articles/1536.pdf |