Probable impact of age and hypoxia on proliferation and microRNA expression profile of bone marrow-derived human mesenchymal stem cells

Decline in the therapeutic potential of bone marrow-derived mesenchymal stem cells (MSC) is often seen with older donors as compared to young. Although hypoxia is known as an approach to improve the therapeutic potential of MSC in term of cell proliferation and differentiation capacity, its effects...

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Bibliographic Details
Main Authors: Norlaily Mohd Ali, Lily Boo, Swee Keong Yeap, Huynh Ky, Dilan A. Satharasinghe, Woan Charn Liew, Han Kiat Ong, Soon Keng Cheong, Tunku Kamarul
Format: Article
Language:English
Published: PeerJ Inc. 2016-01-01
Series:PeerJ
Subjects:
Age
Online Access:https://peerj.com/articles/1536.pdf