Gemcitabine exhibits a suppressive effect on pancreatic cancer cell growth by regulating processing of PVT1 to miR1207

Gemcitabine exhibits a suppressive effect on pancreatic cancer cell growth by regulating processing of PVT1 to miR1207

Gemcitabine serves as a first‐line chemotherapy agent for advanced pancreatic cancer (PC). However, the molecular basis by which gemcitabine exerts its effects is not well‐established, and the targeted genetic pathways remain unclear. Pvt1 oncogene (non‐protein coding) (PVT1) has been reported to be...

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Bibliographic Details
Main Authors: Lei You, Huanyu Wang, Gang Yang, Fangyu Zhao, Jingcheng Zhang, Ziwen Liu, Taiping Zhang, Zhiyong Liang, Changzheng Liu, Yupei Zhao
Format: Article
Language:English
Published: Wiley 2018-12-01
Series:Molecular Oncology
Subjects:
gemcitabine chemotherapy
miRNA processing
pancreatic cancer
PVT1
Online Access:https://doi.org/10.1002/1878-0261.12393

Internet

https://doi.org/10.1002/1878-0261.12393

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