Carbon dioxide inhibits UVB-induced inflammatory response by activating the proton-sensing receptor, GPR65, in human keratinocytes

Carbon dioxide inhibits UVB-induced inflammatory response by activating the proton-sensing receptor, GPR65, in human keratinocytes

Abstract Carbon dioxide (CO2) is the predominant gas molecule emitted during aerobic respiration. Although CO2 can improve blood circulation in the skin via its vasodilatory effects, its effects on skin inflammation remain unclear. The present study aimed to examine the anti-inflammatory effects of...

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Bibliographic Details
Main Authors: Keimon Sayama, Katsuyuki Yuki, Keiichi Sugata, Satoko Fukagawa, Tetsuji Yamamoto, Shigaku Ikeda, Takatoshi Murase
Format: Article
Language:English
Published: Nature Publishing Group 2021-01-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-020-79519-0

Internet

https://doi.org/10.1038/s41598-020-79519-0

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