Integral gene drives for population replacement

Integral gene drives for population replacement

A first generation of CRISPR-based gene drives has now been tested in the laboratory in a number of organisms, including malaria vector mosquitoes. Challenges for their use in the area-wide genetic control of vector-borne disease have been identified, including the development of target site resista...

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Bibliographic Details
Main Authors: Alexander Nash, Giulia Mignini Urdaneta, Andrea K. Beaghton, Astrid Hoermann, Philippos Aris Papathanos, George K. Christophides, Nikolai Windbichler
Format: Article
Language:English
Published: The Company of Biologists 2019-01-01
Series:Biology Open
Subjects:
Gene drive
Population replacement
CRISPR
Genome editing
Population modeling
Online Access:http://bio.biologists.org/content/8/1/bio037762

Internet

http://bio.biologists.org/content/8/1/bio037762

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