SUMO-Specific Protease 2 Suppresses Cell Migration and Invasion through Inhibiting the Expression of MMP13 in Bladder Cancer Cells

SUMO-Specific Protease 2 Suppresses Cell Migration and Invasion through Inhibiting the Expression of MMP13 in Bladder Cancer Cells

Background: SUMO-specific protease 2 (SENP2) is a de-SUMOylation protease family member which has an indispensable role in the regulation of NF-κB transcriptional activation and Wnt signaling. However, whether SENP2 plays a role in tumor metastasis is completely unknown. Methods: Real-time...

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Bibliographic Details
Main Authors: Ming-Yue Tan, Xing-Yu Mu, Bin Liu, Yong Wang, Er-Dun Bao, Jian-Xin Qiu, Yu Fan
Format: Article
Language:English
Published: Cell Physiol Biochem Press GmbH & Co KG 2013-08-01
Series:Cellular Physiology and Biochemistry
Subjects:
SENP2
Metastasis
MMP13
Bladder cancer cells
Online Access:http://www.karger.com/Article/FullText/354458

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http://www.karger.com/Article/FullText/354458

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