Association between ε2/3/4, Promoter Polymorphism (−491A/T, −427T/C, and −219T/G) at the Apolipoprotein E Gene, and Mental Retardation in Children from an Iodine Deficiency Area, China

Background. Several common single-nucleotide polymorphisms (SNPs) at apolipoprotein E (ApoE) have been linked with late onset sporadic Alzheimer’s disease and declining normative cognitive ability in elder people, but we are unclear about their relationship with cognition in children. Results. We st...

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Bibliographic Details
Main Authors: Jun Li, Fuchang Zhang, Yunliang Wang, Yan Wang, Wei Qin, Qinghe Xing, Xueqing Qian, Tingwei Guo, Xiaocai Gao, Lin He, Jianjun Gao
Format: Article
Language:English
Published: Hindawi Limited 2014-01-01
Series:BioMed Research International
Online Access:http://dx.doi.org/10.1155/2014/236702