Rapid methods for the evaluation of fluorescent reporters in tissue clearing and the segmentation of large vascular structures

Summary: Light sheet fluorescence microscopy (LSFM) of large tissue samples does not require mechanical sectioning and allows efficient visualization of spatially complex or rare structures. Therefore, LSFM has become invaluable in developmental and biomedical research. Because sample size may limit...

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Bibliographic Details
Main Authors: Nils Kirschnick, Dominik Drees, Esther Redder, Raghu Erapaneedi, Abel Pereira da Graca, Michael Schäfers, Xiaoyi Jiang, Friedemann Kiefer
Format: Article
Language:English
Published: Elsevier 2021-06-01
Series:iScience
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004221006180