Cancer stem cell immunology: key to understanding tumorigenesis and tumor immune escape?

Cancer stem cell (CSC) biology and tumor immunology have shaped our understanding of tumorigenesis. However, we still do not fully understand why tumors can be contained but not eliminated by the immune system and whether rare CSCs are required for tumor propagation.Long latency or recurrence period...

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Bibliographic Details
Main Authors: Valentin eBruttel, Jörg eWischhusen
Format: Article
Language:English
Published: Frontiers Media S.A. 2014-07-01
Series:Frontiers in Immunology
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fimmu.2014.00360/full