Chlorogenic Acid Promotes Autophagy and Alleviates Salmonella Typhimurium Infection Through the lncRNAGAS5/miR-23a/PTEN Axis and the p38 MAPK Pathway

Chlorogenic Acid Promotes Autophagy and Alleviates Salmonella Typhimurium Infection Through the lncRNAGAS5/miR-23a/PTEN Axis and the p38 MAPK Pathway

BackgroundSalmonella typhimurium (ST) causes several intestinal diseases. Polyphenols including chlorogenic acid (CGA) inhibit pathogenesis.ObjectiveThis study aimed to investigate the mechanisms of CGA in ST infection.MethodsThe intestinal pathological changes and survival rate of ST-infected mice...

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Bibliographic Details
Main Authors: Shirui Tan, Fang Yan, Qingrong Li, Yaping Liang, Junxu Yu, Zhenjun Li, Feifei He, Rongpeng Li, Ming Li
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-11-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
chlorogenic acid
Salmonella typhimurium
lncRNAGAS5
microRNA-23a
PTEN
p38 MAPK
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2020.552020/full

Internet

https://www.frontiersin.org/articles/10.3389/fcell.2020.552020/full

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