Mercury alters endogenous phosphorylation profiles of SYK in murine B cells

Mercury alters endogenous phosphorylation profiles of SYK in murine B cells

Abstract Background Epidemiological evidence and animal models suggest that exposure to low and non-neurotoxic concentrations of mercury may contribute to idiosyncratic autoimmune disease. Since defects in function and signaling in B cells are often associated with autoimmunity, we investigated whet...

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Bibliographic Details
Main Authors: Joseph A. Caruso, Nicholas Carruthers, Namhee Shin, Randal Gill, Paul M. Stemmer, Allen Rosenspire
Format: Article
Language:English
Published: BMC 2017-07-01
Series:BMC Immunology
Subjects:
Mercury
Syk
B cell
Autoimmune disease
Proteomics
Phosphorylation
Online Access:http://link.springer.com/article/10.1186/s12865-017-0221-0

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http://link.springer.com/article/10.1186/s12865-017-0221-0

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