Correlations between Risk Factors for Breast Cancer and Genetic Instability in Cancer Patients—A Clinical Perspective Study

Correlations between Risk Factors for Breast Cancer and Genetic Instability in Cancer Patients—A Clinical Perspective Study

Molecular epidemiological studies have identified several risk factors linking to the genes and external factors in the pathogenesis of breast cancer. In this sense, genetic instability caused by DNA damage and DNA repair inefficiencies are important molecular events for the diagnosis and prognosis...

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Main Authors: Márcia Fernanda Correia Jardim Paz, Marcus Vinícius Oliveira Barros de Alencar, Antonio Luiz Gomes Junior, Keylla da Conceição Machado, Muhammad Torequl Islam, Eunus S. Ali, Manik Chandra Shill, Md. Iqbal Ahmed, Shaikh Jamal Uddin, Ana Maria Oliveira Ferreira da Mata, Ricardo Melo de Carvalho, Kátia da Conceição Machado, André Luiz Pinho Sobral, Felipe Cavalcanti Carneiro da Silva, João Marcelo de Castro e Souza, Daniel Dias Rufino Arcanjo, Paulo Michel Pinheiro Ferreira, Siddhartha Kumar Mishra, Juliana da Silva, Ana Amélia de Carvalho Melo-Cavalcante
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-02-01
Series:Frontiers in Genetics
Subjects:
breast cancer
risk factors
genetic instability
apoptosis
chemotherapy
toxicogenomics
Online Access:http://journal.frontiersin.org/article/10.3389/fgene.2017.00236/full

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http://journal.frontiersin.org/article/10.3389/fgene.2017.00236/full

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