Distinct roles for H4 and H2A.Z acetylation in RNA transcription in African trypanosomes

Histone modification and deposition are key regulators of transcription. Here, Kraus et al. provide a quantitative histone acetylome for Trypanosoma brucei, identify histone modifications enriched at transcription start sites, and show how H4 and H2A.Z acetylation affect histone deposition and trans...

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Bibliographic Details
Main Authors: Amelie J. Kraus, Jens T. Vanselow, Stephanie Lamer, Benedikt G. Brink, Andreas Schlosser, T. Nicolai Siegel
Format: Article
Language:English
Published: Nature Publishing Group 2020-03-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-020-15274-0