Simultaneous in vivo PET/MRI using fluorine-18 labeled Fe3O4@Al(OH)3 nanoparticles: comparison of nanoparticle and nanoparticle-labeled stem cell distribution

Simultaneous in vivo PET/MRI using fluorine-18 labeled Fe3O4@Al(OH)3 nanoparticles: comparison of nanoparticle and nanoparticle-labeled stem cell distribution

Abstract Background Mesenchymal stem cells (MSCs) have shown potential for treatment of different diseases. However, their working mechanism is still unknown. To elucidate this, the non-invasive and longitudinal tracking of MSCs would be beneficial. Both iron oxide-based nanoparticles (Fe3O4 NPs) fo...

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Bibliographic Details
Main Authors: Sarah Belderbos, Manuel Antonio González-Gómez, Frederik Cleeren, Jens Wouters, Yolanda Piñeiro, Christophe M. Deroose, An Coosemans, Willy Gsell, Guy Bormans, Jose Rivas, Uwe Himmelreich
Format: Article
Language:English
Published: SpringerOpen 2020-06-01
Series:EJNMMI Research
Subjects:
Cell tracking
Nanoparticles
Preclinical imaging
Radiolabeling
PET/MRI
Stem cells
Online Access:http://link.springer.com/article/10.1186/s13550-020-00655-9

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http://link.springer.com/article/10.1186/s13550-020-00655-9

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