Nuclear microenvironments modulate transcription from low-affinity enhancers
Transcription factors bind low-affinity DNA sequences for only short durations. It is not clear how brief, low-affinity interactions can drive efficient transcription. Here, we report that the transcription factor Ultrabithorax (Ubx) utilizes low-affinity binding sites in the Drosophila melanogaster...
Main Authors: | Albert Tsai, Anand K Muthusamy, Mariana RP Alves, Luke D Lavis, Robert H Singer, David L Stern, Justin Crocker |
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Format: | Article |
Language: | English |
Published: |
eLife Sciences Publications Ltd
2017-11-01
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Series: | eLife |
Subjects: | |
Online Access: | https://elifesciences.org/articles/28975 |
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