Analysis of polymorphism at site -174 G/C of interleukin-6 promoter region in multiple myeloma

Analysis of polymorphism at site -174 G/C of interleukin-6 promoter region in multiple myeloma

It is well established that interleukin-6 (IL-6) is an essential growth factor for multiple myeloma (MM) and patients with increased IL-6 levels have a poor prognosis. In healthy subjects, the presence of the C allele at a polymorphic site (-174 G/C) of the IL-6 gene is related to low IL-6 levels. I...

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Bibliographic Details
Main Authors: C.R. Duch, M.S. Figueiredo, C. Ribas, M.S.S. Almeida, G.W.B. Colleoni, J.O. Bordin
Format: Article
Language:English
Published: Associação Brasileira de Divulgação Científica 2007-02-01
Series:Brazilian Journal of Medical and Biological Research
Subjects:
Multiple myeloma
Interleukin-6
Polymorphisms
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2007000200014

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http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2007000200014

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