Cognitive Outcomes after DEXmedetomidine sedation in cardiac surgery: CODEX randomised controlled trial protocol

Introduction Older patients undergoing cardiac surgery carry the highest risk for developing major postoperative neurocognitive disorder (postoperative NCD or P-NCD) with up to 25% incidence 3 months after surgery. P-NCD is associated with significant morbidity, mortality, loss of independence, prem...

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Main Authors: Angela Jerath, Frédérick D'Aragon, Philip Jones, George Djaiani, Summer Syed, Lilia Kaustov, Peter Hedlin, Raja Rajamohan, Etienne J. Couture, Amara Singh, Josiane CS Mapplebeck, Sophia Wong, Beverley Anne Orser
Format: Article
Language:English
Published: BMJ Publishing Group 2021-04-01
Series:BMJ Open
Online Access:https://bmjopen.bmj.com/content/11/4/e046851.full