Hyperbaric Oxygen Therapy Alleviates the Autoimmune Encephalomyelitis via the Reduction of IL-17a and GM-Csf Production of Autoreactive T Cells as Well as Boosting the Immunosuppressive IL-10 in the Central Nervous System Tissue Lesions

Hyperbaric Oxygen Therapy Alleviates the Autoimmune Encephalomyelitis via the Reduction of IL-17a and GM-Csf Production of Autoreactive T Cells as Well as Boosting the Immunosuppressive IL-10 in the Central Nervous System Tissue Lesions

Multiple sclerosis (MS) is a chronic autoimmune disease mainly caused by autoreactive T cells, followed by neuronal demyelination and disabling paralysis. Hyperbaric oxygen therapy (HBOT) is usually an adjunct to therapy for the treatment of neurological disorders. However, it remains still controve...

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Bibliographic Details
Main Authors: Hsin-Ying Clair Chiou, Shu-Hung Huang, Chih-Hsing Hung, Su-Min Tsai, Hui-Ru Kuo, Yu-Rui Huang, Jiunn-Wei Wang, Szu-Chia Chen, Chao-Hung Kuo, Deng-Chyang Wu, Shau-Ku Huang, Shih-Hsien Hsu, Ming-Hong Lin
Format: Article
Language:English
Published: MDPI AG 2021-08-01
Series:Biomedicines
Subjects:
hyperbaric oxygen
multiple sclerosis
EAE
CNS
Th17
GM-CSF
Online Access:https://www.mdpi.com/2227-9059/9/8/943

Internet

https://www.mdpi.com/2227-9059/9/8/943

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