Liraglutide improves the beta-cell function without increasing insulin secretion during a mixed meal in patients, who exhibit well-controlled type 2 diabetes and coronary artery disease

Liraglutide improves the beta-cell function without increasing insulin secretion during a mixed meal in patients, who exhibit well-controlled type 2 diabetes and coronary artery disease

Abstract Background Hyperinsulinemia aggravates insulin resistance and cardio-vascular disease. How the insulinotropic glucagon-like peptide-1 receptor agonist liraglutide in a physiologic post-prandial setting may act on pancreatic alpha and beta-cell function in patients with coronary artery disea...

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Bibliographic Details
Main Authors: Christian Anholm, Preman Kumarathurai, Anders Jürs, Lene Rørholm Pedersen, Olav Wendelboe Nielsen, Ole Peter Kristiansen, Mogens Fenger, Jens Juul Holst, Sten Madsbad, Ahmad Sajadieh, Steen Bendix Haugaard
Format: Article
Language:English
Published: BMC 2019-05-01
Series:Diabetology & Metabolic Syndrome
Subjects:
GLP1-receptor agonist
Diabetes mellitus type 2
Beta-cell function
Insulin sensitivity
Meal test
Insulin clearance
Online Access:http://link.springer.com/article/10.1186/s13098-019-0438-6

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http://link.springer.com/article/10.1186/s13098-019-0438-6

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