Cell-Penetrating Peptides: Possibilities and Challenges for Drug Delivery in Vitro and in Vivo

Cell-Penetrating Peptides: Possibilities and Challenges for Drug Delivery in Vitro and in Vivo

In this review, we discuss how cell-penetrating peptides (CPPs) might get access to their intracellular targets. We specifically focus on the challenge of deciding whether the positively-charged CPPs are just bound to the negatively-charged cell surface and subsequently endocytosed or actually tran...

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Bibliographic Details
Main Authors: Tore Skotland, Tore Geir Iversen, Maria Lyngaas Torgersen, Kirsten Sandvig
Format: Article
Language:English
Published: MDPI AG 2015-07-01
Series:Molecules
Subjects:
cell-penetrating peptides
cellular uptake
endocytosis
drug delivery
in vivo dose
pharmaceutical development
Online Access:http://www.mdpi.com/1420-3049/20/7/13313

Internet

http://www.mdpi.com/1420-3049/20/7/13313

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