miR-34a is involved in CSE-induced apoptosis of human pulmonary microvascular endothelial cells by targeting Notch-1 receptor protein

miR-34a is involved in CSE-induced apoptosis of human pulmonary microvascular endothelial cells by targeting Notch-1 receptor protein

Abstract Background Abnormal apoptosis of lung endothelial cells has been observed in emphysematous lung tissue and has been suggested to be an important upstream event in the pathogenesis of chronic obstructive pulmonary disease (COPD). Studies have shown that microRNAs (miRNAs) contribute to the p...

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Bibliographic Details
Main Authors: Ying-Jiao Long, Xiao-Peng Liu, Shan-Shan Chen, Dan-Dan Zong, Yan Chen, Ping Chen
Format: Article
Language:English
Published: BMC 2018-01-01
Series:Respiratory Research
Subjects:
miR-34a
Cigarette smoke extract
Apoptosis
Vascular endothelial cells
Notch-1
Online Access:http://link.springer.com/article/10.1186/s12931-018-0722-2

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http://link.springer.com/article/10.1186/s12931-018-0722-2

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