Functional Analysis of the Glucuronyltransferases GlcAT-P and GlcAT-S of Drosophila melanogaster: Distinct Activities towards the O-linked T-antigen

Functional Analysis of the Glucuronyltransferases GlcAT-P and GlcAT-S of Drosophila melanogaster: Distinct Activities towards the O-linked T-antigen

The Drosophila melanogaster glucuronyltransferases dGlcAT-S and dGlcAT-P were reported to be expressed ubiquitously and results of in vitro activity assays indicate a functional redundancy. We analyzed both transferases in vivo and in vitro and could show significant differences in their activity to...

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Bibliographic Details
Main Authors: Isabelle Breloy, Tilo Schwientek, Deborah Althoff, Marvin Holz, Tim Koppen, Angelika Krupa, Franz-Georg Hanisch
Format: Article
Language:English
Published: MDPI AG 2016-01-01
Series:Biomolecules
Subjects:
glucuronyltransferases
Drosophila melanogaster
N-glycans
O-glycans
mass spectrometry
glycomics
Online Access:http://www.mdpi.com/2218-273X/6/1/8

Internet

http://www.mdpi.com/2218-273X/6/1/8

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