A general framework for quantifying the effects of DNA repair inhibitors on radiation sensitivity as a function of dose

<p>Abstract</p> <p>Purpose</p> <p>Current methods for quantifying effects of DNA repair modifiers on radiation sensitivity assume a constant effect independent of the radiation dose received. The aim of this study was to develop and evaluate a modelling strategy by whic...

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Bibliographic Details
Main Authors: Buffa Francesca M, Bentzen Soeren M, Chalmers Anthony J
Format: Article
Language:English
Published: BMC 2007-07-01
Series:Theoretical Biology and Medical Modelling
Online Access:http://www.tbiomed.com/content/4/1/25