Reduction of the CD16(-)CD56bright NK cell subset precedes NK cell dysfunction in prostate cancer.

BACKGROUND: Natural cytotoxicity, mediated by natural killer (NK) cells plays an important role in the inhibition and elimination of malignant tumor cells. To investigate the immunoregulatory role of NK cells and their potential as diagnostic markers, NK cell activity (NKA) was analyzed in prostate...

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Bibliographic Details
Main Authors: Kyo Chul Koo, Doo Hee Shim, Chang Mo Yang, Saet-Byul Lee, Shi Mun Kim, Tae Young Shin, Kwang Hyun Kim, Ho Geun Yoon, Koon Ho Rha, Jae Myun Lee, Sung Joon Hong
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3817174?pdf=render