Genomic analysis of wig-1 pathways.

BACKGROUND: Wig-1 is a transcription factor regulated by p53 that can interact with hnRNP A2/B1, RNA Helicase A, and dsRNAs, which plays an important role in RNA and protein stabilization. in vitro studies have shown that wig-1 binds p53 mRNA and stabilizes it by protecting it from deadenylation. Fu...

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Bibliographic Details
Main Authors: Yalda Sedaghat, Curt Mazur, Mahyar Sabripour, Gene Hung, Brett P Monia
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3274543?pdf=render