Exosomal linc-ROR mediates crosstalk between cancer cells and adipocytes to promote tumor growth in pancreatic cancer

Exosomal linc-ROR mediates crosstalk between cancer cells and adipocytes to promote tumor growth in pancreatic cancer

Exosomes are emerging as important mediators of the crosstalk between tumor cells and stromal cells in the microenvironment. However, the underlying molecular mechanism of pancreatic cancer (PC)-derived exosomes in the progression of the tumor microenvironment (TME) and crosstalk with adipocytes has...

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Bibliographic Details
Main Authors: Zhaowei Sun, Dong Sun, Yujie Feng, Bingyuan Zhang, Peng Sun, Bin Zhou, Lutao Du, Yunshan Wang, Zhiyao Fan, Jian Yang, Yongzheng Li, Sanyuan Hu, Hanxiang Zhan
Format: Article
Language:English
Published: Elsevier 2021-12-01
Series:Molecular Therapy: Nucleic Acids
Subjects:
exosomes
linc-ROR
pancreatic cancer
adipocytes
coculture system
IL-1β
Online Access:http://www.sciencedirect.com/science/article/pii/S2162253121001426

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http://www.sciencedirect.com/science/article/pii/S2162253121001426

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