Sustained In-Vivo Release of Triptorelin Acetate from a Biodegradable Silica Depot: Comparison to Pamorelin<sup>®</sup> LA

Sustained In-Vivo Release of Triptorelin Acetate from a Biodegradable Silica Depot: Comparison to Pamorelin<sup>®</sup> LA

Triptorelin acetate was encapsulated into silica microparticles by spray-drying a mixture of colloidal silica sol and triptorelin acetate solution. The resulting microparticles were then combined with another silica sol containing silica nanoparticles, which together formed an injectable silica-trip...

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Bibliographic Details
Main Authors: Ari-Pekka Forsback, Panu Noppari, Jesse Viljanen, Jari Mikkola, Mika Jokinen, Lasse Leino, Simon Bjerregaard, Camilla Borglin, Janet Halliday
Format: Article
Language:English
Published: MDPI AG 2021-06-01
Series:Nanomaterials
Subjects:
controlled release
silica hydrogel
silica microparticles
silica nanoparticles
triptorelin
Online Access:https://www.mdpi.com/2079-4991/11/6/1578

Internet

https://www.mdpi.com/2079-4991/11/6/1578

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