Haplotype analysis of TP53 polymorphisms, Arg72Pro and Ins16, in BRCA1 and BRCA2 mutation carriers of French Canadian descent

Haplotype analysis of TP53 polymorphisms, Arg72Pro and Ins16, in BRCA1 and BRCA2 mutation carriers of French Canadian descent

<p>Abstract</p> <p>Background</p> <p>The TP53 polymorphisms Arg72Pro (Ex4+199 G>C) and Ins16 (IVS3+24 ins16) have been proposed to modify risk of breast cancer associated with germline BRCA1 and BRCA2 mutations. Allele frequencies of these polymorphisms were investig...

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Bibliographic Details
Main Authors: Ghadirian Parviz, Maugard Christine, Arcand Suzanna L, Cavallone Luca, Mes-Masson Anne-Marie, Provencher Diane, Tonin Patricia N
Format: Article
Language:English
Published: BMC 2008-04-01
Series:BMC Cancer
Online Access:http://www.biomedcentral.com/1471-2407/8/96

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http://www.biomedcentral.com/1471-2407/8/96

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