15-Deoxy-Δ12,14-Prostaglandin J2 Protects PC12 cells from LPS-Induced Cell Death Through Nrf2 pathway in PPAR-γ Dependent Manner

15-Deoxy-Δ12,14-Prostaglandin J2 Protects PC12 cells from LPS-Induced Cell Death Through Nrf2 pathway in PPAR-γ Dependent Manner

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Introduction: The inflammatory response requires a coordinated integration of various signaling pathway including cyclooxygenase (COX). COX catalyzes the formation of prostaglandins from arachidonic acid. Among prostaglandins, 15-Deoxy-D12, 14-prostaglandin J2 (15d-PGJ2), an endogenous ligand of Per...

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Bibliographic Details
Main Authors: Shahnaz Babaei Abraki, Parnian Eslami, Fariba Khodagholi
Format: Article
Language:English
Published: Iran University of Medical Sciences 2012-02-01
Series:Basic and Clinical Neuroscience
Subjects:
Cyclooxygenase
PPAR-γ
PC12
Nrf2
15d-PGJ2
Neuroprotective.
Online Access:http://bcn.iums.ac.ir/browse.php?a_code=A-10-1-98&slc_lang=en&sid=1

Internet

http://bcn.iums.ac.ir/browse.php?a_code=A-10-1-98&slc_lang=en&sid=1

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