Differential Substrate Usage and Metabolic Fluxes in Francisella tularensis Subspecies holarctica and Francisella novicida

Differential Substrate Usage and Metabolic Fluxes in Francisella tularensis Subspecies holarctica and Francisella novicida

Francisella tularensis is an intracellular pathogen for many animals causing the infectious disease, tularemia. Whereas F. tularensis subsp. holarctica is highly pathogenic for humans, F. novicida is almost avirulent for humans, but virulent for mice. In order to compare metabolic fluxes between the...

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Bibliographic Details
Main Authors: Fan Chen, Kerstin Rydzewski, Erika Kutzner, Ina Häuslein, Eva Schunder, Xinzhe Wang, Kevin Meighen-Berger, Roland Grunow, Wolfgang Eisenreich, Klaus Heuner
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-06-01
Series:Frontiers in Cellular and Infection Microbiology
Subjects:
Francisella
intracellular bacteria
13C-labeling
isotopolog profiling
metabolic adaptation
tularemia
Online Access:http://journal.frontiersin.org/article/10.3389/fcimb.2017.00275/full

Internet

http://journal.frontiersin.org/article/10.3389/fcimb.2017.00275/full

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