Structure–Activity Analysis and Molecular Docking Studies of Coumarins from <i>Toddalia asiatica</i> as<i> </i>Multifunctional Agents for Alzheimer’s Disease

Structure–Activity Analysis and Molecular Docking Studies of Coumarins from <i>Toddalia asiatica</i> as<i> </i>Multifunctional Agents for Alzheimer’s Disease

Coumarins, naturally occurring phytochemicals, display a wide spectrum of biological activities by acting on multiple targets. Herein, nine coumarins from the root of <i>Toddalia asiatica</i> were evaluated for activities related to pathogenesis of Alzheimer’s disease (AD). They were exa...

Full description

Bibliographic Details
Main Authors: Pitchayakarn Takomthong, Pornthip Waiwut, Chavi Yenjai, Bungon Sripanidkulchai, Prasert Reubroycharoen, Ren Lai, Peter Kamau, Chantana Boonyarat
Format: Article
Language:English
Published: MDPI AG 2020-05-01
Series:Biomedicines
Subjects:
acetylcholinesterase
amyloid beta aggregation
neuroprotection
molecular docking
multi-target drug
structure–activity relationship
Online Access:https://www.mdpi.com/2227-9059/8/5/107

Internet

https://www.mdpi.com/2227-9059/8/5/107

Similar Items