A new role for Zinc limitation in bacterial pathogenicity: modulation of α-hemolysin from uropathogenic Escherichia coli

Abstract Metal limitation is a common situation during infection and can have profound effects on the pathogen’s success. In this report, we examine the role of zinc limitation in the expression of a virulence factor in uropathogenic Escherichia coli. The pyelonephritis isolate J96 carries two hlyCA...

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Bibliographic Details
Main Authors: Elsa Velasco, Suning Wang, Marianna Sanet, Jorge Fernández-Vázquez, Daniel Jové, Estibaliz Glaría, Annabel F. Valledor, Thomas V. O’Halloran, Carlos Balsalobre
Format: Article
Language:English
Published: Nature Publishing Group 2018-04-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-018-24964-1