Protection induced by Plasmodium falciparum MSP1(42) is strain-specific, antigen and adjuvant dependent, and correlates with antibody responses.

Protection induced by Plasmodium falciparum MSP1(42) is strain-specific, antigen and adjuvant dependent, and correlates with antibody responses.

Vaccination with Plasmodium falciparum MSP1(42)/complete Freund's adjuvant (FA) followed by MSP1(42)/incomplete FA is the only known regimen that protects Aotus nancymaae monkeys against infection by erythrocytic stage malaria parasites. The role of adjuvant is not defined; however complete FA...

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Bibliographic Details
Main Authors: Jeffrey A Lyon, Evelina Angov, Michael P Fay, JoAnn S Sullivan, Autumn S Girourd, Sally J Robinson, Elke S Bergmann-Leitner, Elizabeth H Duncan, Christian A Darko, William E Collins, Carole A Long, John W Barnwell
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2008-07-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2474699?pdf=render

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http://europepmc.org/articles/PMC2474699?pdf=render

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