Accumulation mode particles and LPS exposure induce TLR-4 dependent and independent inflammatory responses in the lung

Abstract Background Accumulation mode particles (AMP) are formed from engine combustion and make up the inhalable vapour cloud of ambient particulate matter pollution. Their small size facilitates dispersal and subsequent exposure far from their original source, as well as the ability to penetrate a...

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Bibliographic Details
Main Authors: Angela M. Fonceca, Graeme R. Zosky, Elizabeth M. Bozanich, Erika N. Sutanto, Anthony Kicic, Paul S. McNamara, Darryl A. Knight, Peter D. Sly, Debra J. Turner, Stephen M. Stick
Format: Article
Language:English
Published: BMC 2018-01-01
Series:Respiratory Research
Subjects:
PM
LPS
AMP
Online Access:http://link.springer.com/article/10.1186/s12931-017-0701-z