Hyperglycemia aggravates microenvironment hypoxia and promotes the metastatic ability of pancreatic cancer

Background: Diabetes mellitus and pancreatic cancer are intimately related. Our previous studies showed that high levels of blood glucose promote epithelial-mesenchymal transition of pancreatic cancer. In this study, we evaluated the relationship between hyperglycemia and hypoxic tumor microenvironm...

Full description

Bibliographic Details
Main Authors: Wei Li, Han Liu, Weikun Qian, Liang Cheng, Bin Yan, Liang Han, Qinhong Xu, Qingyong Ma, Jiguang Ma
Format: Article
Language:English
Published: Elsevier 2018-01-01
Series:Computational and Structural Biotechnology Journal
Online Access:http://www.sciencedirect.com/science/article/pii/S2001037018301120