Neutrophils increase or reduce parasite burden in Trypanosoma cruzi-infected macrophages, depending on host strain: role of neutrophil elastase.

Neutrophils are involved in the initial steps of most responses to pathogens and are essential components of the innate immune response. Due to the ability to produce and release various soluble mediators, neutrophils may participate in the regulation of the inflammatory response. Little is known ab...

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Main Authors: Tatiana Luna-Gomes, Alessandra A Filardy, Juliana Dutra B Rocha, Debora Decote-Ricardo, Isabel Ferreira LaRocque-de-Freitas, Alexandre Morrot, Patrícia T Bozza, Hugo C Castro-Faria-Neto, George A DosReis, Marise P Nunes, Célio G Freire-de-Lima
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/24599360/?tool=EBI