Cytochrome P450 Monooxygenase-Mediated Metabolic Utilization of Benzo[a]Pyrene by Aspergillus Species

Cytochrome P450 Monooxygenase-Mediated Metabolic Utilization of Benzo[a]Pyrene by Aspergillus Species

We are increasingly exposed to environmental pollutants, including the carcinogen benzo[a]pyrene (BaP), which has prompted extensive research into human metabolism of toxicants. However, little is known about metabolic mechanisms employed by fungi that are able to use some toxic pollutants as the su...

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Bibliographic Details
Main Authors: Erin M. Ostrem Loss, Mi-Kyung Lee, Ming-Yueh Wu, Julia Martien, Wanping Chen, Daniel Amador-Noguez, Colin Jefcoate, Christina Remucal, Seunho Jung, Sun-Chang Kim, Jae-Hyuk Yu
Format: Article
Language:English
Published: American Society for Microbiology 2019-05-01
Series:mBio
Subjects:
Aspergillus
benzo[a]pyrene
catabolic enzyme system
cytochrome P450 monooxygenase
polycyclic aromatic hydrocarbons
velvet regulators
bioremediation
genome-wide expression
high-performance liquid chromatography
metabolomics
molecular genetics
Online Access:https://doi.org/10.1128/mBio.00558-19

Internet

https://doi.org/10.1128/mBio.00558-19

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