Role of hypothalamic MAPK/ERK signaling and central action of FGF1 in diabetes remission

Role of hypothalamic MAPK/ERK signaling and central action of FGF1 in diabetes remission

Summary: The capacity of the brain to elicit sustained remission of hyperglycemia in rodent models of type 2 diabetes following intracerebroventricular (icv) injection of fibroblast growth factor 1 (FGF1) is well established. Here, we show that following icv FGF1 injection, hypothalamic signaling by...

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Bibliographic Details
Main Authors: Jenny M. Brown, Marie A. Bentsen, Dylan M. Rausch, Bao Anh Phan, Danielle Wieck, Huzaifa Wasanwala, Miles E. Matsen, Nikhil Acharya, Nicole E. Richardson, Xin Zhao, Peng Zhai, Anna Secher, Gregory J. Morton, Tune H. Pers, Michael W. Schwartz, Jarrad M. Scarlett
Format: Article
Language:English
Published: Elsevier 2021-09-01
Series:iScience
Subjects:
Molecular biology
Molecular neuroscience
Diabetology
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004221009123

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http://www.sciencedirect.com/science/article/pii/S2589004221009123

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