Identification and localization of minimal MHC-restricted CD8+ T cell epitopes within the <it>Plasmodium falciparum </it>AMA1 protein

Identification and localization of minimal MHC-restricted CD8+ T cell epitopes within the <it>Plasmodium falciparum </it>AMA1 protein

<p>Abstract</p> <p>Background</p> <p><it>Plasmodium falciparum </it>apical membrane antigen-1 (AMA1) is a leading malaria vaccine candidate antigen that is expressed by sporozoite, liver and blood stage parasites. Since CD8+ T cell responses have been implic...

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Bibliographic Details
Main Authors: Sedegah Martha, Kim Yohan, Peters Bjoern, McGrath Shannon, Ganeshan Harini, Lejano Jennylynn, Abot Esteban, Banania Glenna, Belmonte Maria, Sayo Renato, Farooq Fouzia, Doolan Denise L, Regis David, Tamminga Cindy, Chuang Ilin, Bruder Joseph T, King C Richter, Ockenhouse Christian F, Faber Bart, Remarque Edmond, Hollingdale Michael R, Richie Thomas L, Sette Alessandro
Format: Article
Language:English
Published: BMC 2010-08-01
Series:Malaria Journal
Online Access:http://www.malariajournal.com/content/9/1/241

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http://www.malariajournal.com/content/9/1/241

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