Correlation of tryptophan metabolites with connectivity of extended central reward network in healthy subjects.

OBJECTIVE:A growing body of preclinical and clinical literature suggests that brain-gut-microbiota interactions play an important role in human health and disease, including hedonic food intake and obesity. We performed a tripartite network analysis based on graph theory to test the hypothesis that...

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Bibliographic Details
Main Authors: Vadim Osadchiy, Jennifer S Labus, Arpana Gupta, Jonathan Jacobs, Cody Ashe-McNalley, Elaine Y Hsiao, Emeran A Mayer
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC6078307?pdf=render