Heterotypic Signals from Neural HSF-1 Separate Thermotolerance from Longevity

Integrating stress responses across tissues is essential for the survival of multicellular organisms. The metazoan nervous system can sense protein-misfolding stress arising in different subcellular compartments and initiate cytoprotective transcriptional responses in the periphery. Several subcellu...

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Bibliographic Details
Main Authors: Peter M. Douglas, Nathan A. Baird, Milos S. Simic, Sarah Uhlein, Mark A. McCormick, Suzanne C. Wolff, Brian K. Kennedy, Andrew Dillin
Format: Article
Language:English
Published: Elsevier 2015-08-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124715007664