The Pathogenetic Role of the HGF/c-Met System in Papillary Carcinoma of the Thyroid

The MET oncogene encodes for Met protein, a trans-membrane tyrosine kinase identified as the high affinity receptor for hepatocyte growth factor (HGF). Immunohistochemical studies have demonstrated that Met protein is intensely expressed in tumor cells of >95% cases of thyroid papillary carc...

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Bibliographic Details
Main Authors: Luigi Ruco, Stefania Scarpino
Format: Article
Language:English
Published: MDPI AG 2014-10-01
Series:Biomedicines
Subjects:
Online Access:http://www.mdpi.com/2227-9059/2/4/263